研究成果 - 西田　基宏

A protease-activated receptor-1 antagonist protects against podocyte injury in a mouse model of nephropathy

Journal of pharmacological sciences    2017年

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Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Nature communications    2017年

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Exposure to Electrophiles Impairs Reactive Persulfide-Dependent Redox Signaling in Neuronal Cells

Chemical research in toxicology    2017年

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MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts

Journal of the American Heart Association    2017年

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Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Pharmacology & therapeutics    2017年

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Purinergic P2Y6 receptors: A new therapeutic target of age-dependent hypertension

Pharmacological research    2017年

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Purinergic signaling in cardiovascular system

Nihon yakurigaku zasshi. Folia pharmacologica Japonica    2017年

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Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells

Free radical biology & medicine    2017年

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Role of TRPC3 and TRPC6 channels in the myocardial response to stretch: Linking physiology and pathophysiology

Progress in biophysics and molecular biology    2017年

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Stimulation of Adenosine A2B Receptor Inhibits Endothelin-1-Induced Cardiac Fibroblast Proliferation and α-Smooth Muscle Actin Synthesis Through the cAMP/Epac/PI3K/Akt-Signaling Pathway

Frontiers in pharmacology    2017年

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TRPC3 Channels in Cardiac Fibrosis

Frontiers in cardiovascular medicine    2017年

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TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy

JCI insight    2017年

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TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice

Scientific reports    2017年

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Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells

Scientific Reports    2016年

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Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension

Science signaling    2016年

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Redox signaling regulated by an electrophilic cyclic nucleotide and reactive cysteine persulfides

Archives of biochemistry and biophysics    2016年

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Redox signaling regulated by electrophiles and reactive sulfur species

Journal of clinical biochemistry and nutrition    2016年

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Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds

Molecular pharmacology    2016年

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Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner

Molecular endocrinology (Baltimore, Md.)    2016年

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TRPC3 amplifies B-cell receptor-induced ERK signalling via protein kinase D-dependent Rap1 activation

The Biochemical journal    2016年

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